Clinical Value of the N-S-P Scheme for Diagnosing Vulvar Dermatosis (DATRIV Study, Part 2)
Vesna Harni,
Damir Babic,
Suzana Ljubojevic-Hadzavdic,
Dubravko Barisic
Issue:
Volume 10, Issue 3, May 2022
Pages:
159-166
Received:
5 April 2022
Accepted:
23 April 2022
Published:
29 April 2022
Abstract: The DATRIV study aimed to create a basis for developing standard outcome measures in vulvoscopy to facilitate the diagnosis and treatment of vulvar discomfort. For this purpose, the three rings vulvoscopy (TRIV) was introduced, and the vulvoscopy index and N-S-P scheme were designed as outcome parameters. In this paper, the clinical value of collecting and managing data obtained during TRIV in normal and patients with chronic vulvar distress was carefully examined by introducing the N-S-P scheme. Complex ISSVD vulvodynia pattern questionnaire and TRIV form data were methodically performed for data gathering. The collected data were explored using StatSoft (Dell, Austin, Texas), Statistica 12 (TIBCO®, Palo Alto, CA) and SPSS 20 (IBM, Armonk, NY). Ethical permission for the study was acquired from the Institutional Review Board of the Polyclinic Harni, and all patients gave written informed consent. In addition to TRIV, lesions specific to vulvar dermatosis were detected in 82 patients. Histopathology diagnosed vulvar dermatosis at the first biopsy in 72 patients. The resulting difference of ten patients consisted of patients with early vulvar dermatosis. Six of these ten subjects were diagnosed with vulvar dermatosis on a second biopsy during the study period. Statistical tests did not show a significant difference between normal findings or the presence of any type of lesion (nonspecific and specific) concerning the three vulvar rings, except in ten patients with early vulvar dermatoses. The N-S-P scheme accurately recognized the disease in all patients showing 100% sensitivity in detecting vulvar dermatoses. Patients without histopathological verified vulvar dermatosis at the first biopsy were classified as false positives, so the specificity of the test was 96.1%. Overall, the diagnostic accuracy of the N-S-P scheme in detecting vulvar dermatosis was 96.9%. Positive and negative predictive values were 0.88 and 1.00, respectively. The N-S-P scheme and TRIV are convincing clinical tests to detect vulvar dermatoses. Differences between vulvoscopy and histopathological diagnostics imply a lack of specificity of tissue transformations within early forms of vulvar dermatoses sufficient to distinguish them microscopically from normal findings. Consequently, early dermatoses could be a critical area for proposing this test. ClinicalTrials.gov Identifier: NCT02732145.
Abstract: The DATRIV study aimed to create a basis for developing standard outcome measures in vulvoscopy to facilitate the diagnosis and treatment of vulvar discomfort. For this purpose, the three rings vulvoscopy (TRIV) was introduced, and the vulvoscopy index and N-S-P scheme were designed as outcome parameters. In this paper, the clinical value of collec...
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Introduction of DMPA-SC and Self-injection (AI) in the City of Conakry (Guinea) in Time of COVID-19 in 2021
Soumah Aboubacar Fode Momo,
Moussa Kantara Camara,
Ibrahima Koussy Bah,
Conte Ibrahima,
Sylla Ibrahima
Issue:
Volume 10, Issue 3, May 2022
Pages:
167-170
Received:
7 June 2022
Accepted:
25 June 2022
Published:
30 June 2022
Abstract: Context: The maternal mortality rate in Guinea remains high at 550/100,000 live births. Contraceptive prevalence is still low with 11% for women in union, unmet need was 22% with a fertility rate of 4.8. With this in mind, the DMPA-SC was introduced in Guinea in 2018 and then scaled up to 2020. The objective was to study the supply of DMPA- SC and AI services in the health districts of Conakry in the time of COVID-19. Methods: This was a descriptive, cross-sectional, prospective recruitment study, from March 1 to November 30, 2021 in public health facilities and from June 1 to November 30, 2021 in private health facilities; it involved new users of DMPA SC and AI in these facilities, the review and validation of FP data from the facilities, and post-training follow-up was carried out by telephone or in person. The data were collected in a whatsAPP platform and processed using Excel software. Results: We counted 2279 new users, including 1474 for DMPA-SC and 271 DMPA-SC AI in 28 public health facilities and 383 DMPA-SC and 151DPMA-SC AI in 30 private clinics. The practice of self-injection was more dominant in private clinics (70%) than in public facilities (36%). Conclusion: Private clinics appear to be an opportunity to increase contraceptive prevalence in Guinea.
Abstract: Context: The maternal mortality rate in Guinea remains high at 550/100,000 live births. Contraceptive prevalence is still low with 11% for women in union, unmet need was 22% with a fertility rate of 4.8. With this in mind, the DMPA-SC was introduced in Guinea in 2018 and then scaled up to 2020. The objective was to study the supply of DMPA- SC and ...
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