Journal of Gynecology and Obstetrics

Volume 1, Issue 1, July 2013

  • The Proteasome Subunit LMP2/b1i In the Female Genital System

    Takuma Hayashi, Takuma Hayashi, Takuma Hayashi, Akiko Horiuchi, Kenji Sano, Gal Gur, Gal Gur, Hiroyuki Aburatani, Tomoyuki Ichimura, Nobuo Yaegashi, Yae Kanai, Dorit Zharhary, Dorit Zharhary, Susumu Tonegawa, Ikuo Konishi

    Issue: Volume 1, Issue 1, July 2013
    Pages: 1-6
    Received: 28 May 2013
    Published: 30 June 2013
    Abstract: Protein degradation by the ubiquitin-proteasome system is central to cell homeostasis and survival. Defects in this process are associated with diseases such as cancer and neurodegenerative disorders. The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arr... Show More