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Venous Trhomboembolic Diseases in Gestants Followed at the Centre Médical Diamant in Lubumbashi: Analysis of Diagnosis and Therapeutic Elements

Received: 1 February 2022    Accepted: 16 March 2022    Published: 24 August 2022
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Abstract

Pregnancy is one of the main risk factors for the development of venous thromboembolic disease (VTED). The objective of this work was to analyze the diagnostic and therapeutic elements of venous thrombosis in pregnant women followed at the Centre médical Diamant in Lubumbashi (CMDL). This is a descriptive cross-sectional study over a period of 27 months at CMDL in DR Congo, including all pregnant women followed for venous thrombosis during the study period. Data analysis was done by SPSS 22.0 software. The prevalence of VTED was 5.2% with a mean age of 27 ± 3 years (Extreme: 21 to 42 years). The telltale signs were dominated by asymmetric swelling of the lower limb (27.3%) and the main location was femoro-popliteal (63.6%). Superficial venous thrombosis was predominant with 54.5%. The diagnosis of VTE was supported by measurement of D-dimer in 100% of cases, confirmed by Doppler ultrasound in 81.8% of cases. Associated factors were non-O blood group (45.5%), history of miscarriages (27.3%), family history (18.2%), age over 35 years (18.2%), multiparity (27.3%) and gestational diabetes (18.2%). The treatment combined low molecular weight heparin in 72.7%. The mean duration of treatment was 28 days (range: 18-42 days). The outcome was favorable in 63.6% of cases. Venous thrombosis in pregnancy remains a major challenge in our environment because the risk factors and specific determinants are not known, there is no preventive or curative protocol adapted to our working conditions. Further, more in-depth studies are needed to optimize and rationalize care.

Published in Journal of Gynecology and Obstetrics (Volume 10, Issue 4)
DOI 10.11648/j.jgo.20221004.18
Page(s) 211-216
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Pregnancy, Venous Thrombosis, DR Congo

References
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Cite This Article
  • APA Style

    Mubinda Kiopin Patrick, Augustin Kibonge Mukakala, Iteke Fefe Rivain, Shaddy Mahfoud, Muanda Panzu Patrick, et al. (2022). Venous Trhomboembolic Diseases in Gestants Followed at the Centre Médical Diamant in Lubumbashi: Analysis of Diagnosis and Therapeutic Elements. Journal of Gynecology and Obstetrics, 10(4), 211-216. https://doi.org/10.11648/j.jgo.20221004.18

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    ACS Style

    Mubinda Kiopin Patrick; Augustin Kibonge Mukakala; Iteke Fefe Rivain; Shaddy Mahfoud; Muanda Panzu Patrick, et al. Venous Trhomboembolic Diseases in Gestants Followed at the Centre Médical Diamant in Lubumbashi: Analysis of Diagnosis and Therapeutic Elements. J. Gynecol. Obstet. 2022, 10(4), 211-216. doi: 10.11648/j.jgo.20221004.18

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    AMA Style

    Mubinda Kiopin Patrick, Augustin Kibonge Mukakala, Iteke Fefe Rivain, Shaddy Mahfoud, Muanda Panzu Patrick, et al. Venous Trhomboembolic Diseases in Gestants Followed at the Centre Médical Diamant in Lubumbashi: Analysis of Diagnosis and Therapeutic Elements. J Gynecol Obstet. 2022;10(4):211-216. doi: 10.11648/j.jgo.20221004.18

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  • @article{10.11648/j.jgo.20221004.18,
      author = {Mubinda Kiopin Patrick and Augustin Kibonge Mukakala and Iteke Fefe Rivain and Shaddy Mahfoud and Muanda Panzu Patrick and Mwape Besa Baltfazar and Prosper Kalenga Muenze},
      title = {Venous Trhomboembolic Diseases in Gestants Followed at the Centre Médical Diamant in Lubumbashi: Analysis of Diagnosis and Therapeutic Elements},
      journal = {Journal of Gynecology and Obstetrics},
      volume = {10},
      number = {4},
      pages = {211-216},
      doi = {10.11648/j.jgo.20221004.18},
      url = {https://doi.org/10.11648/j.jgo.20221004.18},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20221004.18},
      abstract = {Pregnancy is one of the main risk factors for the development of venous thromboembolic disease (VTED). The objective of this work was to analyze the diagnostic and therapeutic elements of venous thrombosis in pregnant women followed at the Centre médical Diamant in Lubumbashi (CMDL). This is a descriptive cross-sectional study over a period of 27 months at CMDL in DR Congo, including all pregnant women followed for venous thrombosis during the study period. Data analysis was done by SPSS 22.0 software. The prevalence of VTED was 5.2% with a mean age of 27 ± 3 years (Extreme: 21 to 42 years). The telltale signs were dominated by asymmetric swelling of the lower limb (27.3%) and the main location was femoro-popliteal (63.6%). Superficial venous thrombosis was predominant with 54.5%. The diagnosis of VTE was supported by measurement of D-dimer in 100% of cases, confirmed by Doppler ultrasound in 81.8% of cases. Associated factors were non-O blood group (45.5%), history of miscarriages (27.3%), family history (18.2%), age over 35 years (18.2%), multiparity (27.3%) and gestational diabetes (18.2%). The treatment combined low molecular weight heparin in 72.7%. The mean duration of treatment was 28 days (range: 18-42 days). The outcome was favorable in 63.6% of cases. Venous thrombosis in pregnancy remains a major challenge in our environment because the risk factors and specific determinants are not known, there is no preventive or curative protocol adapted to our working conditions. Further, more in-depth studies are needed to optimize and rationalize care.},
     year = {2022}
    }
    

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  • TY  - JOUR
    T1  - Venous Trhomboembolic Diseases in Gestants Followed at the Centre Médical Diamant in Lubumbashi: Analysis of Diagnosis and Therapeutic Elements
    AU  - Mubinda Kiopin Patrick
    AU  - Augustin Kibonge Mukakala
    AU  - Iteke Fefe Rivain
    AU  - Shaddy Mahfoud
    AU  - Muanda Panzu Patrick
    AU  - Mwape Besa Baltfazar
    AU  - Prosper Kalenga Muenze
    Y1  - 2022/08/24
    PY  - 2022
    N1  - https://doi.org/10.11648/j.jgo.20221004.18
    DO  - 10.11648/j.jgo.20221004.18
    T2  - Journal of Gynecology and Obstetrics
    JF  - Journal of Gynecology and Obstetrics
    JO  - Journal of Gynecology and Obstetrics
    SP  - 211
    EP  - 216
    PB  - Science Publishing Group
    SN  - 2376-7820
    UR  - https://doi.org/10.11648/j.jgo.20221004.18
    AB  - Pregnancy is one of the main risk factors for the development of venous thromboembolic disease (VTED). The objective of this work was to analyze the diagnostic and therapeutic elements of venous thrombosis in pregnant women followed at the Centre médical Diamant in Lubumbashi (CMDL). This is a descriptive cross-sectional study over a period of 27 months at CMDL in DR Congo, including all pregnant women followed for venous thrombosis during the study period. Data analysis was done by SPSS 22.0 software. The prevalence of VTED was 5.2% with a mean age of 27 ± 3 years (Extreme: 21 to 42 years). The telltale signs were dominated by asymmetric swelling of the lower limb (27.3%) and the main location was femoro-popliteal (63.6%). Superficial venous thrombosis was predominant with 54.5%. The diagnosis of VTE was supported by measurement of D-dimer in 100% of cases, confirmed by Doppler ultrasound in 81.8% of cases. Associated factors were non-O blood group (45.5%), history of miscarriages (27.3%), family history (18.2%), age over 35 years (18.2%), multiparity (27.3%) and gestational diabetes (18.2%). The treatment combined low molecular weight heparin in 72.7%. The mean duration of treatment was 28 days (range: 18-42 days). The outcome was favorable in 63.6% of cases. Venous thrombosis in pregnancy remains a major challenge in our environment because the risk factors and specific determinants are not known, there is no preventive or curative protocol adapted to our working conditions. Further, more in-depth studies are needed to optimize and rationalize care.
    VL  - 10
    IS  - 4
    ER  - 

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Author Information
  • Department of Gyneco-Obstetrics, University of Lubumbashi, Lubumbashi, Democratic Republic of the Congo

  • Department of General Surgery, Université Officielle de Bukavu, Bukau, Democratic Republic of the Congo

  • Centre Medical Diament of Lubumbashi, Lubumbashi, Democratic Republic of the Congo

  • Centre Medical Diament of Lubumbashi, Lubumbashi, Democratic Republic of the Congo

  • Centre Medical Diament of Lubumbashi, Lubumbashi, Democratic Republic of the Congo

  • Department of Anesthesia-Resuscitation, University of Lubumbashi, Lubumbashi, Democratic Republic of the Congo

  • Department of Gyneco-Obstetrics, University of Lubumbashi, Lubumbashi, Democratic Republic of the Congo

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