Volume 7, Issue 5, September 2019, Page: 125-129
Benign Reactive Xanthogranuloma of the Cervix, a Rare Tumor of the Female Genital Tract in a Case Report
Georges Wehbe, Department of Obstetrics and Gynecology, Rafik Hariri University Hospital (RHUH), Beirut, Lebanon; Department of Obstetrics and Gynecology, Lebanese University, Beirut, Lebanon
Jessie Darido, Department of Obstetrics and Gynecology, Rafik Hariri University Hospital (RHUH), Beirut, Lebanon; Department of Obstetrics and Gynecology, Lebanese University, Beirut, Lebanon
Mohammad Khaled Ramadan, Department of Obstetrics and Gynecology, Rafik Hariri University Hospital (RHUH), Beirut, Lebanon; Department of Obstetrics and Gynecology, Lebanese University, Beirut, Lebanon
Rabih Chahine, Department of Obstetrics and Gynecology, Rafik Hariri University Hospital (RHUH), Beirut, Lebanon
Ahmad Estaitieh, Department of Obstetrics and Gynecology, Rafik Hariri University Hospital (RHUH), Beirut, Lebanon
Ahmad Lakis, Department of Radiology, Rafik Hariri University Hospital (RHUH), Beirut, Lebanon
Omar Sheikh, Department of Radiology, Rafik Hariri University Hospital (RHUH), Beirut, Lebanon
Khaled Habib, Department of Pathology, Rafik Hariri University Hospital (RHUH), Beirut, Lebanon
Saad El Daou, Department of General Surgery, Lebanese University, Beirut, Lebanon
Nicolas Haddad, Department of Obstetrics and Gynecology, Lebanese University, Beirut, Lebanon
Received: Jul. 11, 2019;       Accepted: Aug. 19, 2019;       Published: Sep. 2, 2019
DOI: 10.11648/j.jgo.20190705.11      View  92      Downloads  18
Abstract
Xanthogranuloma is a benign disorder that is considered to be a very rare event when it happens in the female reproductive organs. It can mimic adnexal tumors clinically and radiologically. The vulva, the vagina, the cervix or the endometrium can be involved. It is a process during which the tissues are infiltrated by lipid-laden histiocytes mixed with lymphocytes, plasma cells and polymorphonuclear leucocytes. In this article, we are reporting a rare case of an adult xanthogranulomatous inflammation of the uterine cervix with a detailed clinical, pathologic, radiologic and follow up data. A 46-year-old lady presented with vaginal bleeding, dysmenorrhea and pelvic heaviness. She underwent a diagnostic dilation and curetting at a peripheral hospital due to increased endometrial thickness on ultrasound. Then, she was misdiagnosed with a diffused large B cell lymphoma (Non-Hodgkin Lymphoma) and was treated with two cycles of chemotherapy. At our department, abdominopelvic ultrasound and CT scan showed a 10 x 9.4 cm round cervical mass associated with hydronephrosis. A cervical biopsy was also taken turned back with a pseudotumoral xanthogranulomatous cervicitis. Consequently, a hysterectomy with bilateral salpingo oophorectomy was decided and performed taking into consideration the possibility of a coexistent associated malignancy of the reproductive organs. In contrast with juvenile xanthogranuloma, we could not have expected from our case of adult xanthogranuloma to regress. Finally, more studies and reported cases are needed in order to assess the adequate management and utility of radiotherapy/chemotherapy in such cases of Xanthogranulomatous inflammation of the female genital tract.
Keywords
Cervical Adult Xanthogranuloma, Pseudotumoral Xanthogranulomatous Cervicitis, Associated Malignancy, Female Genital Tract
To cite this article
Georges Wehbe, Jessie Darido, Mohammad Khaled Ramadan, Rabih Chahine, Ahmad Estaitieh, Ahmad Lakis, Omar Sheikh, Khaled Habib, Saad El Daou, Nicolas Haddad, Benign Reactive Xanthogranuloma of the Cervix, a Rare Tumor of the Female Genital Tract in a Case Report, Journal of Gynecology and Obstetrics. Vol. 7, No. 5, 2019, pp. 125-129. doi: 10.11648/j.jgo.20190705.11
Copyright
Copyright © 2019 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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