Volume 7, Issue 3, May 2019, Page: 72-75
HPV Viral Test for Primary Cervical Cancer Screening at the Nabil Choucair Health Center in Senegalese Women 30 to 65 Years Old
Omar Gassama, Gynecological and Obstetric Clinic, Aristide Le Dantec University Hospital, Dakar, Senegal
Babacar Faye, Gynecological and Obstetric Clinic, Aristide Le Dantec University Hospital, Dakar, Senegal
Mor Cisse, Gynecological and Obstetric Clinic, Aristide Le Dantec University Hospital, Dakar, Senegal
Mamadou Seye, Gynecological and Obstetric Clinic, Aristide Le Dantec University Hospital, Dakar, Senegal
Lamine Gueye, Gynecological and Obstetric Clinic, Aristide Le Dantec University Hospital, Dakar, Senegal
Babacar Biaye, Gynecological and Obstetric Clinic, Aristide Le Dantec University Hospital, Dakar, Senegal
Mamadou Lamine Cisse, Gynecological and Obstetric Clinic, Aristide Le Dantec University Hospital, Dakar, Senegal
Philippe Marc Moreira, Gynecological and Obstetric Clinic, Aristide Le Dantec University Hospital, Dakar, Senegal
Alassane Diouf, Gynecological and Obstetric Clinic, Aristide Le Dantec University Hospital, Dakar, Senegal
Moussa Moro Guindo, Gynecological and Obstetric Clinic, Aristide Le Dantec University Hospital, Dakar, Senegal
Alioune Dieye, Gynecological and Obstetric Clinic, Aristide Le Dantec University Hospital, Dakar, Senegal
Jean Charles Moreau, Gynecological and Obstetric Clinic, Aristide Le Dantec University Hospital, Dakar, Senegal
Received: Mar. 28, 2019;       Accepted: May 15, 2019;       Published: Jun. 4, 2019
DOI: 10.11648/j.jgo.20190703.13      View  90      Downloads  14
Abstract
The objective of this study was to describe demographics of patients who had benefited from a cervical cancer screening by an HPV viral test; to specify the protocol used to establish diagnosis using the test results; and to describe treatment and follow-up methods on positively tested patients. This was an descriptive prospective cohort study conducted at the Nabil Choucair health center and the Military Hospital of Ouakam from May 1st 2017 to January 30th 2018. The study involved 144 patients who had benefited from an HPV ABBOOT m2000 viral test. The studied parameters included socio-demographic characteristics, clinical aspects, test results, diagnosis, treatment and follow-up. The data was collected on a form and the statistical analysis was performed using Epi-info 7. In this study we collected 144 women. The mean age of the patients was 39.9 years. Patients were predominantly married (84%) and mostly housewives (48.1%), with slightly more than half (55.6%) of them who attended school. More than half of the patients 61.8% were under contraception. Almost all patients (92.4%) were of child bearing age. The average gravidity was 3.4 with an average parity of 2.7. The average age at marriage was 22.6 years mostly in a monogamous household (56.8%). The average age at first intercourse was 22.1. The average age at first pregnancy was 23.9. More than ¾ of women (78.3%) had one partner; however, note that 21.7% of the patients had 2 or more partners. The viral test was positive in 17 patients (11.8%). Papillomaviruses 16 and 18 were the most encountered (56%). Colposcopy was normal and satisfactory in 9 patients (53%), 2 patients had abnormal minor changes (11.7%) and 2 cases had major changes (11.7%). Cervical biopsy was performed in 2 patients (11.7%), histology showed CIN3 and micro invasive carcinoma. For those patients a conization was performed. The postoperative course was simple. The HPV viral test for primary cervical cancer screening offers opportunities and is possible in developing countries such as Senegal despite its limited means.
Keywords
HPV Viral Test, Nabil Choucair Health Center, Cervical Cancer Screening
To cite this article
Omar Gassama, Babacar Faye, Mor Cisse, Mamadou Seye, Lamine Gueye, Babacar Biaye, Mamadou Lamine Cisse, Philippe Marc Moreira, Alassane Diouf, Moussa Moro Guindo, Alioune Dieye, Jean Charles Moreau, HPV Viral Test for Primary Cervical Cancer Screening at the Nabil Choucair Health Center in Senegalese Women 30 to 65 Years Old, Journal of Gynecology and Obstetrics. Vol. 7, No. 3, 2019, pp. 72-75. doi: 10.11648/j.jgo.20190703.13
Copyright
Copyright © 2019 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Reference
[1]
Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jamel A. Global Cancer Stastistics 2018: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. Cancer J Clin 2018; 68: 394-424.
[2]
Harald Zur Hausen, Wolf Meinhof, Wiltrud Scheiber, George W Bornkamm Attempts to detect virus-specific DNA in human tumors. I. Nucleid acid hybridizations with complementary RNA of human wart virus International Journal of cancer volume 13, Issue 5, 1974; 650-656.
[3]
T. M. Zohoncon, C. Ouédraogo, et al. Molecular Epidemiology of High-Risk Human Papillomavirus in High-Grade Cervical Intraepithelial Neoplasia and in Cervical Cancer in Parakou, Republic of Benin. Pakistan Journal of Biological Sciences 2016; 10.3923 (8): 1-8.
[4]
C. M. R. Ouédraogo, F. W. Djigma, et al. Épidémiologie et caractérisation des génotypes de papillomavirus humain dans une population de femmes à Ouagadougou. Journal de Gynécologie Obstétrique et Biologie de la Reproduction 2011; 40, 633—638.
[5]
Chan. CC. Les facteurs associés au dépistage des cancers du col utérin dans une population mutualiste Rev Epidemiol Sante Publique. 2005; 53: 69-75.
[6]
Tebeu. PM. Lésions précancéreuses du col utérin en zone rurale: étude transversale. Med Afr Noire. 2005; 52: 27-31.
[7]
Rebecca. SH. HIV Infection as a Risk Factor for Cervical Cancer and Cervical Intraepithelial Neoplasia in Senegal. cancer epidemiology, biomarkers et prevention. 2009; 18 (9).
[8]
Gassama. O. Bilan des activités de colposcopie au service de gynécologie-obstétrique du CHU A. Le Dantec: FMPOS Dakar, Année; 2011 thèse N° 43.
[9]
Khaoula. B. Les lésions de haut grade du col utérin. FMP FES; Année 2016 thèse N°13.
[10]
Samaké. B. Lésions précancéreuses et cancéreuses du col de l’utérus au centre de santé de référence de la commune V du district de Bamako. FMPOS Bamako Année 2010 thèse N°47.
[11]
Lachiri. B. Etude prospective sur la place de la colposcopie dans le dépistage des lésions intraépithéliales du col utérin à propos de 565 cas à Temara. FMP Rabat; Année 2009 thèse N°240.
[12]
Millogo. FT. Dépistage du cancer du col utérin dans le district sanitaire (Burkina Faso) par biopsie des volontaires après applications d’acide acétique et de lugol. Bulletin Société Pathologie Exotique. 2004; 977 (2): 135-8.
[13]
N’golet. A. Les néoplasies cervicales intra-épithéliales à Brazzaville, Congo. Analyse de situation. Ann Path. 2004; 24: 324-8.
[14]
El Hadji Seydou Mbaye, Tarik Gheit, Ahmadou Dem, Sandrine McKay‐Chopin, Ndeye Coumba Toure‐Kane, Souleymane Mboup, Massimo Tommasino. Human papillomavirus infection in women in four regions of Sénégal J. Med. Virol. 86: 248–256, 2014.
[15]
Bardin A, Vaccarella S, Clifford GM, Lissowska J, Rekosz M, Bobkiewicz P, et al. Human papillomavirus infection in women with and without cervical cancer in Warsaw, Poland. Eur J Cancer 2008; 44: 557—64.
[16]
Reithmuller, Ramanah R, Pretet JL, Mougin C. Intégration du test HPV dans le dépistage primaire? JGOBR 2008; 375: 5139—51.
[17]
Hammouda D, Clifford GM, Pallardy S, Ayyach G, Chekiri A, Boudrich A, et al. Human papillomavirus infection in a population-based sample of women in Algiers, Algeria. Int J Cancer 2011; 128: 2224—9, doi: 10.1002/ijc.25539.
[18]
Sellors J W, Sankaranarayan R. Colposcopie et traitement des néoplasies cervicales intra-épithéliales: Manuel à l’usage des débutants. Centre International de Recherche sur le Cancer, Lyon 2004; p 579.
[19]
Bulkmans NW, Rozendaal L, Voorhorst FJ, et al. Long-term protective effect of high-risk human papillomavirus testing in population-based cervical screening. Br J Cancer 2005; 92: 1800-2.
[20]
Baay M, Verhoeven V. Intégrer un test HPV dans le dépistage du cancer du col? Minerva F 2008; 7 (7): 108-9.
Browse journals by subject