Volume 6, Issue 1, January 2018, Page: 1-5
Dynamic Thiol/Disulphide Homeostasis in Patients with Vaginitis
Raziye Desdicioglu, Obstetrics and Gynecology Department, Faculty of Medicine, Yildirim Beyazit University, Ankara, Turkey
Melahat Yildirim, Obstetrics and Gynecology Department, Faculty of Medicine, Yildirim Beyazit University, Ankara, Turkey
Betul Ozbek, Biochemistry Department, Faculty of Medicine, Yildirim Beyazit University, Ankara, Turkey
Gokhan Kılıc, Obstetrics and Gynecology Department, Faculty of Medicine, Yildirim Beyazit University, Ankara, Turkey
Ozcan Erel, Biochemistry Department, Faculty of Medicine, Yildirim Beyazit University, Ankara, Turkey
Ayse Filiz Yavuz, Obstetrics and Gynecology Department, Faculty of Medicine, Yildirim Beyazit University, Ankara, Turkey
Received: Dec. 5, 2017;       Accepted: Dec. 15, 2017;       Published: Jan. 16, 2018
DOI: 10.11648/j.jgo.20180601.11      View  2010      Downloads  124
This study investigated the thiol-disulphide balance in vaginitis, which is a local inflammatory condition, through the use of a new method. A cross-sectional study involving 82 women (45 women with vaginitis and 37 women in control group) was conducted at Ataturk Education and Research Hospital, Ankara, Turkey from February 2016 to April 2016. Their ages varied between 19-75 years (mean: 42.8±11.6), were incorporated into the study. Thiol – disulphide parameters were measured and the obtained results were compared. The results showed that the serum disulphide level and disulphide/native thiol ratio in the group with vaginitis (p = 0.03 and p = 0.04) and the native thiol/total thiol ratio in the control group was higher (p = 0.03). In this study, it was shown that serum dynamic thiol-disulphide balance in the women with vaginitis had varied. Although vaginitis is a localized infectious inflammatory condition, the increase in the systemic oxidative stress is important. This study is the first article in the literature that investigates the relationship between dynamic thiol-disulphide balance and vaginitis.
Disulphide, Thiol, Vaginitis
To cite this article
Raziye Desdicioglu, Melahat Yildirim, Betul Ozbek, Gokhan Kılıc, Ozcan Erel, Ayse Filiz Yavuz, Dynamic Thiol/Disulphide Homeostasis in Patients with Vaginitis, Journal of Gynecology and Obstetrics. Vol. 6, No. 1, 2018, pp. 1-5. doi: 10.11648/j.jgo.20180601.11
Copyright © 2018 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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