Volume 5, Issue 3, May 2017, Page: 42-45
Antimicrobial Prophylaxis for Women with First Trimester Vaginal Bleeding Could Reduce the Rate of Miscarriage
Kaima Abdullah Frass, Department of Obstetrics and Gynecology, Faculty of Medicine, Sana'a University, Sana’a, Yemen
Amat-Al Karem Ali Al Huri, Department of Obstetrics and Gynecology, Faculty of Medicine, Sana'a University, Sana’a, Yemen
Abdelrahman Hasan Al Harazi, Department of Obstetrics and Gynecology, Faculty of Medicine, Thamar University, Sana’a, Yemen
Received: May 3, 2017;       Accepted: May 11, 2017;       Published: Jun. 28, 2017
DOI: 10.11648/j.jgo.20170503.12      View  2340      Downloads  117
This is a prospective study conducted to examine the possible benefit of antibiotic prophylaxis in reducing the symptoms of threatened miscarriage as well as decreasing the rate of progression into spontaneous miscarriage in women with first trimester vaginal bleeding. This study was conducted at Al Thawra General Hospital over a year (from Jan. to Dec 2016). Ninety-two women with threatened miscarriage during the first trimester were included (case group) and compared to 90 pregnant women without vaginal bleeding with similar parity and gestational age. Amoxicillin-clavulanate drug was given for all cases of the study group during vaginal bleeding. Both groups were monitored up to 28 weeks gestational age. Among 92 women with threatened miscarriage, only three cases (3.2%) had spontaneous loss (P < 0.001). Vaginal bleeding was significantly relieved within 3 days of antibiotic administration (P < 0.00). Results of this study give evidence that antibiotic prophylaxis for women with threatened miscarriage reduces the amount and duration of vaginal bleeding, and decreases the rate of progression into spontaneous miscarriage.
Women, First-Trimester Bleeding, Miscarriage, Antibiotic
To cite this article
Kaima Abdullah Frass, Amat-Al Karem Ali Al Huri, Abdelrahman Hasan Al Harazi, Antimicrobial Prophylaxis for Women with First Trimester Vaginal Bleeding Could Reduce the Rate of Miscarriage, Journal of Gynecology and Obstetrics. Vol. 5, No. 3, 2017, pp. 42-45. doi: 10.11648/j.jgo.20170503.12
Copyright © 2017 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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