Prevalence and Associated Factors of Hepatitis B Virus Infection Among Pregnant Women Attending Antenatal Care at Felegehiwot Hospital, Bahir Dar, Ethiopia

Abyot Terefe Teshome; Ebrahim Abdela Siraj; Beselam Gizachew Astatekie; Litegebew Yitayeh Gelaw; Dagninet Derebe; Haylemariam Adera Bayleyegn; Oumer Abdu Muhie; Ashagrachew Tewabe Yayehrad; Adise Adem Ahmed; Adugna Tasew Tebabal

doi:doi:10.11648/j.jgo.20231104.14

Prevalence and Associated Factors of Hepatitis B Virus Infection Among Pregnant Women Attending Antenatal Care at Felegehiwot Hospital, Bahir Dar, Ethiopia

Abyot Terefe Teshome, Ebrahim Abdela Siraj, Beselam Gizachew Astatekie, Litegebew Yitayeh Gelaw, Dagninet Derebe, Haylemariam Adera Bayleyegn, Oumer Abdu Muhie, Ashagrachew Tewabe Yayehrad, Adise Adem Ahmed, Adugna Tasew Tebabal

Published in Journal of Gynecology and Obstetrics (Volume 11, Issue 4)

Received: 10 July 2023 Accepted: 24 July 2023 Published: 5 August 2023

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Abstract

Background: Hepatitis B virus is one of the major infectious diseases and caused by a small enveloped DNA virus. Globally, 360 million people have a chronic HBV infection, and greater than three fourth of these live in the Western Pacific Region and Africa, considered as a region with high endemicity. Hepatitis B virus infection during pregnancy has a high risk of vertical transmission and is harmful to both the mother and the newborn. There is a lack of information regarding the prevalence of HBV infection and its contributing factors among pregnant women in Bahir Dar City. Objectives: To assess the prevalence and associated factors of Hepatitis B virus infection among pregnant women who had Antenatal Care services at Felegehiwot Comprehensive specialized Hospital in Bahir Dar City. Methods: Institution based cross sectional study design was employed at Felegehiwot Comprehensive specialized Hospital among 221 mothers. Systematic random sampling technique was used to select the study participants and data was collected using structured questionnaire by face-to-face interview and chart reviews. Data were entered into SPSS version 25 and cleaned, coded and analyzed. Bivariate and multi-variable logistic regression analysis was used. P<0.05 was used to express the statistical significance of the variables. Result: Prevalence of HBV infection is found to be 4.5% among study participants. History of blood transfusion [AOR=13.4, 95% CI (1.79-101.36)], genital mutilation [AOR=11.2, 95% CI (1.20-104.3)] and body tattooing [AOR= 6.6, 95% CI (1.29-33.7)] were the significantly associated determinant factors for HBV infection. Conclusion: The prevalence of the HBV was intermediate, according to WHO classification criteria. History of blood transfusion, body tattooing and genital mutilation were the determinant factors identified in this study. The study's recommendations involve maintaining sterility while taking blood samples for transfusion, eliminating risky cultural behaviors, and promoting community awareness regarding transmission and prevention techniques.

Published in	Journal of Gynecology and Obstetrics (Volume 11, Issue 4)
DOI	10.11648/j.jgo.20231104.14
Page(s)	100-105
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Prevalence, HBV, Pregnant Women, Antenatal Care

References

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[2]	Kheiri L, Makvandi S. The prevalence of hepatitis B surface antigen (HBsAg) and its influencing factors in pregnant women referring to healthcare centers of Dehloran, Iran in 2011-2012. Journal of Midwifery and Reproductive Health. 2015; 3 (3): 424-9.
[3]	Mac P, Suleiman A, Airiohuodion P. High prevalence of hepatitis B virus infection among pregnant women attending antenatal care in Central Nigeria. J Infect Dis Epidemiol. 2019; 5 (1): 068.
[4]	Moghaddasifar I, Lankarani KB, Moosazadeh M, Afshari M, Malary M. Prevalence of hepatitis B virus infection among pregnant women in Iran: a systematic review and Meta-analysis. Iranian Journal of Cancer Prevention. 2016; 9 (6).
[5]	Kebede KM, Abateneh DD, Belay AS. Hepatitis B virus infection among pregnant women in Ethiopia: a systematic review and Meta-analysis of prevalence studies. BMC infectious diseases. 2018; 18: 1-9.
[6]	Tiruye G, Shiferaw K, Tadesse F. Seroprevalence of hepatitis B virus infection and associated factors among pregnant women attended antenatal care services in Harar City, Eastern Ethiopia. Journal of Women's Health Care. 2018; 7 (3): 3-10.
[7]	Tesfu MA, Habtemariam TT, Belay NB. Risk factors associated with Hepatitis B virus infection among pregnant women attending public hospitals in Addis Ababa, Ethiopia. Plos one. 2023; 18 (4): e0284646.
[8]	Kinfe H, Sendo EG, Gebremedhin KB. Prevalence of Hepatitis B Virus Infection and Factors Associated with Hepatitis B Virus Infection Among Pregnant Women Presented to Antenatal Care Clinics at Adigrat General Hospital in Northern Ethiopia. International Journal of Women's Health. 2021: 119-27.
[9]	Awole M, Gebre-Selassie S. Seroprevalence of HBsAg and its risk factors amoung pregnant women in Jimma, Southwest Ethiopia. Ethiopian Journal of Health Development. 2005; 19 (1): 45-50.
[10]	Atalay AA, Abebe RK, Dadhi AE, Bededa WK. Seroprevalence of hepatitis B virus among pregnant women attending Antenatal care in Dilla University Referral Hospital Gedio Zone, Ethiopia; health facility based cross-sectional study. Plos one. 2021; 16 (3): e0249216.
[11]	Mekonnen R, Admasu D, Belete M. Sero-Prevalence of Hepatitis B Virus and associated factors among pregnant mothers attending antenatal care in Public Health Facilities, Dire Dawa. J Med Microb Diagn. 2018; 7 (281): 2161-0703.1000281.
[12]	Dortey BA, Anaba EA, Lassey A, Damale N, Maya ET. Seroprevalence of Hepatitis B virus infection and associated factors among pregnant women at Korle-Bu Teaching Hospital, Ghana. Plos one. 2020; 15 (4): e0232208.
[13]	Mbaawuaga E, Enenebeaku M, Okopi J. Hepatitis B virus (HBV) infection among pregnant women in Makurdi, Nigeria. African Journal of Biomedical Research. 2008; 11 (2).
[14]	Souza MT, Pinho TLRd, Santos MDC, Santos Ad, Monteiro VL, Fonsêca LMB, et al. Prevalence of hepatitis B among pregnant women assisted at the public maternity hospitals of São Luís, Maranhão, Brazil. Brazilian Journal of Infectious Diseases. 2012; 16: 517-20.
[15]	Seo DH, Whang DH, Song EY, Han KS. Occult hepatitis B virus infection and blood transfusion. World journal of hepatology. 2015; 7 (3): 600.
[16]	Fopa D, Candotti D, Tagny CT, Doux C, Mbanya D, Murphy EL, et al. Occult hepatitis B infection among blood donors from Yaoundé, Cameroon. Blood Transfusion. 2019; 17 (6): 403.
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Abyot Terefe Teshome, Ebrahim Abdela Siraj, Beselam Gizachew Astatekie, Litegebew Yitayeh Gelaw, Dagninet Derebe, et al. (2023). Prevalence and Associated Factors of Hepatitis B Virus Infection Among Pregnant Women Attending Antenatal Care at Felegehiwot Hospital, Bahir Dar, Ethiopia. Journal of Gynecology and Obstetrics, 11(4), 100-105. https://doi.org/10.11648/j.jgo.20231104.14

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ACS Style

Abyot Terefe Teshome; Ebrahim Abdela Siraj; Beselam Gizachew Astatekie; Litegebew Yitayeh Gelaw; Dagninet Derebe, et al. Prevalence and Associated Factors of Hepatitis B Virus Infection Among Pregnant Women Attending Antenatal Care at Felegehiwot Hospital, Bahir Dar, Ethiopia. J. Gynecol. Obstet. 2023, 11(4), 100-105. doi: 10.11648/j.jgo.20231104.14

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AMA Style

Abyot Terefe Teshome, Ebrahim Abdela Siraj, Beselam Gizachew Astatekie, Litegebew Yitayeh Gelaw, Dagninet Derebe, et al. Prevalence and Associated Factors of Hepatitis B Virus Infection Among Pregnant Women Attending Antenatal Care at Felegehiwot Hospital, Bahir Dar, Ethiopia. J Gynecol Obstet. 2023;11(4):100-105. doi: 10.11648/j.jgo.20231104.14

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@article{10.11648/j.jgo.20231104.14,
  author = {Abyot Terefe Teshome and Ebrahim Abdela Siraj and Beselam Gizachew Astatekie and Litegebew Yitayeh Gelaw and Dagninet Derebe and Haylemariam Adera Bayleyegn and Oumer Abdu Muhie and Ashagrachew Tewabe Yayehrad and Adise Adem Ahmed and Adugna Tasew Tebabal},
  title = {Prevalence and Associated Factors of Hepatitis B Virus Infection Among Pregnant Women Attending Antenatal Care at Felegehiwot Hospital, Bahir Dar, Ethiopia},
  journal = {Journal of Gynecology and Obstetrics},
  volume = {11},
  number = {4},
  pages = {100-105},
  doi = {10.11648/j.jgo.20231104.14},
  url = {https://doi.org/10.11648/j.jgo.20231104.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20231104.14},
  abstract = {Background: Hepatitis B virus is one of the major infectious diseases and caused by a small enveloped DNA virus. Globally, 360 million people have a chronic HBV infection, and greater than three fourth of these live in the Western Pacific Region and Africa, considered as a region with high endemicity. Hepatitis B virus infection during pregnancy has a high risk of vertical transmission and is harmful to both the mother and the newborn. There is a lack of information regarding the prevalence of HBV infection and its contributing factors among pregnant women in Bahir Dar City. Objectives: To assess the prevalence and associated factors of Hepatitis B virus infection among pregnant women who had Antenatal Care services at Felegehiwot Comprehensive specialized Hospital in Bahir Dar City. Methods: Institution based cross sectional study design was employed at Felegehiwot Comprehensive specialized Hospital among 221 mothers. Systematic random sampling technique was used to select the study participants and data was collected using structured questionnaire by face-to-face interview and chart reviews. Data were entered into SPSS version 25 and cleaned, coded and analyzed. Bivariate and multi-variable logistic regression analysis was used. PResult: Prevalence of HBV infection is found to be 4.5% among study participants. History of blood transfusion [AOR=13.4, 95% CI (1.79-101.36)], genital mutilation [AOR=11.2, 95% CI (1.20-104.3)] and body tattooing [AOR= 6.6, 95% CI (1.29-33.7)] were the significantly associated determinant factors for HBV infection. Conclusion: The prevalence of the HBV was intermediate, according to WHO classification criteria. History of blood transfusion, body tattooing and genital mutilation were the determinant factors identified in this study. The study's recommendations involve maintaining sterility while taking blood samples for transfusion, eliminating risky cultural behaviors, and promoting community awareness regarding transmission and prevention techniques.},
 year = {2023}
}

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TY  - JOUR
T1  - Prevalence and Associated Factors of Hepatitis B Virus Infection Among Pregnant Women Attending Antenatal Care at Felegehiwot Hospital, Bahir Dar, Ethiopia
AU  - Abyot Terefe Teshome
AU  - Ebrahim Abdela Siraj
AU  - Beselam Gizachew Astatekie
AU  - Litegebew Yitayeh Gelaw
AU  - Dagninet Derebe
AU  - Haylemariam Adera Bayleyegn
AU  - Oumer Abdu Muhie
AU  - Ashagrachew Tewabe Yayehrad
AU  - Adise Adem Ahmed
AU  - Adugna Tasew Tebabal
Y1  - 2023/08/05
PY  - 2023
N1  - https://doi.org/10.11648/j.jgo.20231104.14
DO  - 10.11648/j.jgo.20231104.14
T2  - Journal of Gynecology and Obstetrics
JF  - Journal of Gynecology and Obstetrics
JO  - Journal of Gynecology and Obstetrics
SP  - 100
EP  - 105
PB  - Science Publishing Group
SN  - 2376-7820
UR  - https://doi.org/10.11648/j.jgo.20231104.14
AB  - Background: Hepatitis B virus is one of the major infectious diseases and caused by a small enveloped DNA virus. Globally, 360 million people have a chronic HBV infection, and greater than three fourth of these live in the Western Pacific Region and Africa, considered as a region with high endemicity. Hepatitis B virus infection during pregnancy has a high risk of vertical transmission and is harmful to both the mother and the newborn. There is a lack of information regarding the prevalence of HBV infection and its contributing factors among pregnant women in Bahir Dar City. Objectives: To assess the prevalence and associated factors of Hepatitis B virus infection among pregnant women who had Antenatal Care services at Felegehiwot Comprehensive specialized Hospital in Bahir Dar City. Methods: Institution based cross sectional study design was employed at Felegehiwot Comprehensive specialized Hospital among 221 mothers. Systematic random sampling technique was used to select the study participants and data was collected using structured questionnaire by face-to-face interview and chart reviews. Data were entered into SPSS version 25 and cleaned, coded and analyzed. Bivariate and multi-variable logistic regression analysis was used. PResult: Prevalence of HBV infection is found to be 4.5% among study participants. History of blood transfusion [AOR=13.4, 95% CI (1.79-101.36)], genital mutilation [AOR=11.2, 95% CI (1.20-104.3)] and body tattooing [AOR= 6.6, 95% CI (1.29-33.7)] were the significantly associated determinant factors for HBV infection. Conclusion: The prevalence of the HBV was intermediate, according to WHO classification criteria. History of blood transfusion, body tattooing and genital mutilation were the determinant factors identified in this study. The study's recommendations involve maintaining sterility while taking blood samples for transfusion, eliminating risky cultural behaviors, and promoting community awareness regarding transmission and prevention techniques.
VL  - 11
IS  - 4
ER  -

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Author Information

Abyot Terefe Teshome

Department of Internal Medicine, Felege Hiwot Comprehensive Specialized Hospital, Bahir Dar, Ethiopia
Ebrahim Abdela Siraj

Department of Pharmacy, School of Health Sciences, College of Medicine and Health Science, Bahir Dar University, Bahir Dar, Ethiopia
Beselam Gizachew Astatekie

Department of Public Health, GAMBY Medical and Business College (MPH), Bahir Dar, Ethiopia
Litegebew Yitayeh Gelaw

Public Health and Chief Expert, Medical Laboratory Technologist MedX Diagnostic, Bahir Dar, Ethiopia
Dagninet Derebe

Department of Pharmacy, College of Medicine and Health Science, Bahir Dar University, Bahir Dar, Ethiopia
Haylemariam Adera Bayleyegn

Department of Internal Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia
Oumer Abdu Muhie

Department of Internal Medicine, Gamby Teaching General Hospital, Bahir Dar, Ethiopia
Ashagrachew Tewabe Yayehrad

Department of Pharmacy, School of Health Sciences, College of Medicine and Health Science, Bahir Dar University, Bahir Dar, Ethiopia
Adise Adem Ahmed

Department of Public Health, Gamby Teaching General Hospital, Bahir Dar, Ethiopia
Adugna Tasew Tebabal

Department of Medicine, Dean of GAMBY Medical and Business College, Bahir Dar, Ethiopia

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APA Style

Abyot Terefe Teshome, Ebrahim Abdela Siraj, Beselam Gizachew Astatekie, Litegebew Yitayeh Gelaw, Dagninet Derebe, et al. (2023). Prevalence and Associated Factors of Hepatitis B Virus Infection Among Pregnant Women Attending Antenatal Care at Felegehiwot Hospital, Bahir Dar, Ethiopia. Journal of Gynecology and Obstetrics, 11(4), 100-105. https://doi.org/10.11648/j.jgo.20231104.14

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ACS Style

Abyot Terefe Teshome; Ebrahim Abdela Siraj; Beselam Gizachew Astatekie; Litegebew Yitayeh Gelaw; Dagninet Derebe, et al. Prevalence and Associated Factors of Hepatitis B Virus Infection Among Pregnant Women Attending Antenatal Care at Felegehiwot Hospital, Bahir Dar, Ethiopia. J. Gynecol. Obstet. 2023, 11(4), 100-105. doi: 10.11648/j.jgo.20231104.14

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AMA Style

Abyot Terefe Teshome, Ebrahim Abdela Siraj, Beselam Gizachew Astatekie, Litegebew Yitayeh Gelaw, Dagninet Derebe, et al. Prevalence and Associated Factors of Hepatitis B Virus Infection Among Pregnant Women Attending Antenatal Care at Felegehiwot Hospital, Bahir Dar, Ethiopia. J Gynecol Obstet. 2023;11(4):100-105. doi: 10.11648/j.jgo.20231104.14

Copy | Download

@article{10.11648/j.jgo.20231104.14,
  author = {Abyot Terefe Teshome and Ebrahim Abdela Siraj and Beselam Gizachew Astatekie and Litegebew Yitayeh Gelaw and Dagninet Derebe and Haylemariam Adera Bayleyegn and Oumer Abdu Muhie and Ashagrachew Tewabe Yayehrad and Adise Adem Ahmed and Adugna Tasew Tebabal},
  title = {Prevalence and Associated Factors of Hepatitis B Virus Infection Among Pregnant Women Attending Antenatal Care at Felegehiwot Hospital, Bahir Dar, Ethiopia},
  journal = {Journal of Gynecology and Obstetrics},
  volume = {11},
  number = {4},
  pages = {100-105},
  doi = {10.11648/j.jgo.20231104.14},
  url = {https://doi.org/10.11648/j.jgo.20231104.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20231104.14},
  abstract = {Background: Hepatitis B virus is one of the major infectious diseases and caused by a small enveloped DNA virus. Globally, 360 million people have a chronic HBV infection, and greater than three fourth of these live in the Western Pacific Region and Africa, considered as a region with high endemicity. Hepatitis B virus infection during pregnancy has a high risk of vertical transmission and is harmful to both the mother and the newborn. There is a lack of information regarding the prevalence of HBV infection and its contributing factors among pregnant women in Bahir Dar City. Objectives: To assess the prevalence and associated factors of Hepatitis B virus infection among pregnant women who had Antenatal Care services at Felegehiwot Comprehensive specialized Hospital in Bahir Dar City. Methods: Institution based cross sectional study design was employed at Felegehiwot Comprehensive specialized Hospital among 221 mothers. Systematic random sampling technique was used to select the study participants and data was collected using structured questionnaire by face-to-face interview and chart reviews. Data were entered into SPSS version 25 and cleaned, coded and analyzed. Bivariate and multi-variable logistic regression analysis was used. PResult: Prevalence of HBV infection is found to be 4.5% among study participants. History of blood transfusion [AOR=13.4, 95% CI (1.79-101.36)], genital mutilation [AOR=11.2, 95% CI (1.20-104.3)] and body tattooing [AOR= 6.6, 95% CI (1.29-33.7)] were the significantly associated determinant factors for HBV infection. Conclusion: The prevalence of the HBV was intermediate, according to WHO classification criteria. History of blood transfusion, body tattooing and genital mutilation were the determinant factors identified in this study. The study's recommendations involve maintaining sterility while taking blood samples for transfusion, eliminating risky cultural behaviors, and promoting community awareness regarding transmission and prevention techniques.},
 year = {2023}
}

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TY  - JOUR
T1  - Prevalence and Associated Factors of Hepatitis B Virus Infection Among Pregnant Women Attending Antenatal Care at Felegehiwot Hospital, Bahir Dar, Ethiopia
AU  - Abyot Terefe Teshome
AU  - Ebrahim Abdela Siraj
AU  - Beselam Gizachew Astatekie
AU  - Litegebew Yitayeh Gelaw
AU  - Dagninet Derebe
AU  - Haylemariam Adera Bayleyegn
AU  - Oumer Abdu Muhie
AU  - Ashagrachew Tewabe Yayehrad
AU  - Adise Adem Ahmed
AU  - Adugna Tasew Tebabal
Y1  - 2023/08/05
PY  - 2023
N1  - https://doi.org/10.11648/j.jgo.20231104.14
DO  - 10.11648/j.jgo.20231104.14
T2  - Journal of Gynecology and Obstetrics
JF  - Journal of Gynecology and Obstetrics
JO  - Journal of Gynecology and Obstetrics
SP  - 100
EP  - 105
PB  - Science Publishing Group
SN  - 2376-7820
UR  - https://doi.org/10.11648/j.jgo.20231104.14
AB  - Background: Hepatitis B virus is one of the major infectious diseases and caused by a small enveloped DNA virus. Globally, 360 million people have a chronic HBV infection, and greater than three fourth of these live in the Western Pacific Region and Africa, considered as a region with high endemicity. Hepatitis B virus infection during pregnancy has a high risk of vertical transmission and is harmful to both the mother and the newborn. There is a lack of information regarding the prevalence of HBV infection and its contributing factors among pregnant women in Bahir Dar City. Objectives: To assess the prevalence and associated factors of Hepatitis B virus infection among pregnant women who had Antenatal Care services at Felegehiwot Comprehensive specialized Hospital in Bahir Dar City. Methods: Institution based cross sectional study design was employed at Felegehiwot Comprehensive specialized Hospital among 221 mothers. Systematic random sampling technique was used to select the study participants and data was collected using structured questionnaire by face-to-face interview and chart reviews. Data were entered into SPSS version 25 and cleaned, coded and analyzed. Bivariate and multi-variable logistic regression analysis was used. PResult: Prevalence of HBV infection is found to be 4.5% among study participants. History of blood transfusion [AOR=13.4, 95% CI (1.79-101.36)], genital mutilation [AOR=11.2, 95% CI (1.20-104.3)] and body tattooing [AOR= 6.6, 95% CI (1.29-33.7)] were the significantly associated determinant factors for HBV infection. Conclusion: The prevalence of the HBV was intermediate, according to WHO classification criteria. History of blood transfusion, body tattooing and genital mutilation were the determinant factors identified in this study. The study's recommendations involve maintaining sterility while taking blood samples for transfusion, eliminating risky cultural behaviors, and promoting community awareness regarding transmission and prevention techniques.
VL  - 11
IS  - 4
ER  -

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