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Sociodemographic Attribute and Clinical Outcomes of Ectopic Pregnancy Managed in a Tertiary Hospital in Southern Nigeria

Received: 2 September 2022    Accepted: 4 October 2022    Published: 21 October 2022
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Abstract

The most frequent gynaecological emergency is ectopic pregnancy, and it has high rates of maternal morbidity and mortality particularly when intervention is delayed. This study focused on the socio-demographic attributes and clinical outcomes of patients managed for ectopic pregnancy at the University of Benin Teaching Hospital (UBTH), Benin City, Nigeria. All cases of ectopic pregnancy in UBTH from January 2017 to December 2019 were retrospectively studied. Information on their presentation, clinical management and outcomes of treatment were retrieved from the hospital records library, ward registers, departmental computerized data set and theatre records. The data was analyzed using SPSS version 22. There were 6738 deliveries, 2365 gynaecological admissions and 141 cases of ectopic pregnancy in the period under review. Ectopic pregnancy (EP) constituted 2.1% of all deliveries and 5.97% of all gynaecological admissions. The peak age of incidence was 25 – 29 years. The majority of the patients (58.2%) were single and they were mostly undergraduates (41.8%). The majority (81.6%) presented with ruptured ectopic pregnancy. Shock was the commonest presentation (59.1%), and 60.1% had a blood transfusion. Salpingectomy was the mainstay of treatment (86.3%). For the unruptured cases selected for medical management, the success rate was 84.2%. Ectopic pregnancy is a common gynaecological emergency and still poses a major challenge due to late presentation. Previous induced abortion and pelvic inflammatory disease are the major risk factors for EP. Increasing awareness of prevention, early presentation, and risk of morbidity and mortality will help to reduce this scourge.

Published in Journal of Gynecology and Obstetrics (Volume 10, Issue 5)
DOI 10.11648/j.jgo.20221005.13
Page(s) 231-235
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Ectopic Pregnancy, Gynaecological Emergency, Salpingectomy, Blood Transfusion, Risk Factors

References
[1] Shayesteh P, somayeh M, and Mahnaz A. Main Risk Factors For Ectopic Pregnancy: A case control Study in a Sample of Iranian Women. Int J Fertil Steril. 2014; 8 (2): 147-54.
[2] Andrew H. Ectopic Pregnancy in Gynaecology by Ten teachers. 20th Edition. Taylor & Francis Group, LLC. 2017; 109-110.
[3] Davor J. Ectopic Pregnancy in Dewhurst’s Textbook of Obstetrics & Gynaecology, Eighth Edition. D. Keith Edmonds (Ed). John Wiley and Sons, Ltd. 2012; 76-87.
[4] Kwawukume EY, Ekele BA. Ectopic gestation in Comprehensive Gynaecology in the Tropics. 2nd edition. AG Literature Centre ltd, Accra 2017; 97-106.
[5] Creanga AA, Syverson C, Seed K, Callaghan WM. pregnancy-related mortality in the United state 2011-2013. Obstet Gynecol 2017; 130: 366-73.
[6] Jiang Y, Chen J, Zhou H, Zheng M, Han K, Ling J, Zhu X, Tang X, Li R, Hong Y. Management and obstetric outcomes of 17 heterotopic interstitial pregnancies. BMC Pregnancy and Childbirth. 2018 Dec; 18 (1): 1-6.
[7] Alptekin H, Dal Y: Heterotopic pregnancy following IVF-ET: successful treatment with salpingostomy under spinal anesthesia and continuation of intrauterine twin pregnancy. Arch Gynecol Obstet. 2014, 289: 911-14. 10.1007/s00404-013-3099-y.
[8] Surette A, Dunham SM. Ectopic Pregnancy in Current Diagnosis & Treatment; Obstetrics & Gynaecology. 11th Edition. McGraw-Hill Companies, Inc 2013; 242-249.
[9] Yadav A, Prakash A, Sharma C, Pegu B, Saha MK. Trends of ectopic pregnancies in Andaman and Nicobar Islands. Int J Reprod Contracept Obstet Gynaecol 2017; 6: 15-20.
[10] Storeide O, Veholmen M, Eide M, Bergsjø P, Sandvei R. The incidence of ectopic pregnancy in Hordaland County, Norway 1976–1993. Acta obstetricia et gynecologica Scandinavica. 1997; 76: 345-9.
[11] Oppong AA, Agbemenyah HY, Afeke I, Jamfaru I, Attachie I, Orish VN. Ectopic pregnancy in a referral hospital in the Volta region of Ghana west Africa. Open Access Library Journal. 2016 Sep 30; 3 (9): 1-9.
[12] Akaha GO, Agida TE, Onafowokan O. Ectopic pregnancy in Nigeria's federal capital territory: A six-year review. Niger J Med. 2012; 21 (2): 241-5.
[13] Udigwe GO, Umeononihu OS, Mbachu II. Ectopic pregnancy: a 5-year review of cases at Nnamdi Azikiwe University Teaching Hospital (NAUTH) Nnewi. Nig Med J. 1; 51 (4): 160-3.
[14] Gharoro EP, Igbafe AA. Ectopic Pregnancy revisited in Benin City, Nigeria: analysis of 152 cases. Acta Obstet Gynaecol Scand 2002 Dec; 81 (12): 1139-43.
[15] Westrom L, Bengtsson LPH, Mardh PA. Incidence, trends and risks of ectopic pregnancy in a population of women. BMJ 1981; 282: 15–18.
[16] Stovall TG. Early pregnancy loss and ectopic pregnancy. In: Berek and Novak’s Gynecology, 14th edition. Berek JS (Ed). Lippincott Williams & Wilkins 2007; 604–635.
[17] Ugboma HAA, Oputa OA, Orazulike NC, Allagoa DO. Ectopic Pregnancy: Recent Experience in a Tertiary Hospital, South-Southern Nigeria. Int J Trop Dis Health 2017; 21: 1-6.
[18] Anorlu RI, Oluwole A, Abudu OO, Adebajo S. Risk factors for ectopic pregnancy in Lagos, Nigeria. Acta Obstet Gynecol Scand 2005; 84: 184–188.
[19] Adewunmi AA, Adewunmi KA, Tayo OA, Aletan OE. Ectopic Pregnancy in Lagos State University Teaching Hospital, Ikeja, Lagos. Nigeria. Ajol 2010; 58: 1-2.
[20] Cleland K, Raymond E, Trussell J, Cheng L, Zhu H. Ectopic pregnancy and emergency contraceptive Pills: a systematic review. Obstet Gynecol 2010; 115: 1263-6.
[21] Emergency contraception. American College of Obstetrician and Gynaecologist. Obstet Gynecol 2015; 126 (152): e1-11.
[22] Aziken ME, Okonkwo CA, Aderoba A, Onakewhor UE. Medical Management of Unruptured Ectopic Pregnancy in a Tertiary Care Facility in Nigeria. Mary Slessor Journal of Med 2010; 10: 2.
[23] Shaw JT, Dey SK, Critchley HO, Horme AW. Current knowledge of the aetiology of human tubal ectopic pregnancy. Human reprod update 2010; 16: 32-44.
[24] Gwegbu AO, Eleje GU, Okpala BC. An appraisal of the management of Ectopic pregnancy in Nigeria Tertiary Hospital. Ann Med Health Sci Res 2013; 3 (2): 166-170.
[25] Panti A, Ikechukwu NE, Lukman OO, Yakubu A, Egondu SC, Tanko BA. Ectopic pregnancy at Usman Danfodiya University Teaching hospital Sokoto: a ten-year review. Ann Niger Med 2012; 9 (2): 87-91.
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  • APA Style

    Kehinde Osazee, Peter Waibode Alabrah, Chidinma Joy Anya. (2022). Sociodemographic Attribute and Clinical Outcomes of Ectopic Pregnancy Managed in a Tertiary Hospital in Southern Nigeria. Journal of Gynecology and Obstetrics, 10(5), 231-235. https://doi.org/10.11648/j.jgo.20221005.13

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    ACS Style

    Kehinde Osazee; Peter Waibode Alabrah; Chidinma Joy Anya. Sociodemographic Attribute and Clinical Outcomes of Ectopic Pregnancy Managed in a Tertiary Hospital in Southern Nigeria. J. Gynecol. Obstet. 2022, 10(5), 231-235. doi: 10.11648/j.jgo.20221005.13

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    AMA Style

    Kehinde Osazee, Peter Waibode Alabrah, Chidinma Joy Anya. Sociodemographic Attribute and Clinical Outcomes of Ectopic Pregnancy Managed in a Tertiary Hospital in Southern Nigeria. J Gynecol Obstet. 2022;10(5):231-235. doi: 10.11648/j.jgo.20221005.13

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  • @article{10.11648/j.jgo.20221005.13,
      author = {Kehinde Osazee and Peter Waibode Alabrah and Chidinma Joy Anya},
      title = {Sociodemographic Attribute and Clinical Outcomes of Ectopic Pregnancy Managed in a Tertiary Hospital in Southern Nigeria},
      journal = {Journal of Gynecology and Obstetrics},
      volume = {10},
      number = {5},
      pages = {231-235},
      doi = {10.11648/j.jgo.20221005.13},
      url = {https://doi.org/10.11648/j.jgo.20221005.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20221005.13},
      abstract = {The most frequent gynaecological emergency is ectopic pregnancy, and it has high rates of maternal morbidity and mortality particularly when intervention is delayed. This study focused on the socio-demographic attributes and clinical outcomes of patients managed for ectopic pregnancy at the University of Benin Teaching Hospital (UBTH), Benin City, Nigeria. All cases of ectopic pregnancy in UBTH from January 2017 to December 2019 were retrospectively studied. Information on their presentation, clinical management and outcomes of treatment were retrieved from the hospital records library, ward registers, departmental computerized data set and theatre records. The data was analyzed using SPSS version 22. There were 6738 deliveries, 2365 gynaecological admissions and 141 cases of ectopic pregnancy in the period under review. Ectopic pregnancy (EP) constituted 2.1% of all deliveries and 5.97% of all gynaecological admissions. The peak age of incidence was 25 – 29 years. The majority of the patients (58.2%) were single and they were mostly undergraduates (41.8%). The majority (81.6%) presented with ruptured ectopic pregnancy. Shock was the commonest presentation (59.1%), and 60.1% had a blood transfusion. Salpingectomy was the mainstay of treatment (86.3%). For the unruptured cases selected for medical management, the success rate was 84.2%. Ectopic pregnancy is a common gynaecological emergency and still poses a major challenge due to late presentation. Previous induced abortion and pelvic inflammatory disease are the major risk factors for EP. Increasing awareness of prevention, early presentation, and risk of morbidity and mortality will help to reduce this scourge.},
     year = {2022}
    }
    

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    AU  - Kehinde Osazee
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    AB  - The most frequent gynaecological emergency is ectopic pregnancy, and it has high rates of maternal morbidity and mortality particularly when intervention is delayed. This study focused on the socio-demographic attributes and clinical outcomes of patients managed for ectopic pregnancy at the University of Benin Teaching Hospital (UBTH), Benin City, Nigeria. All cases of ectopic pregnancy in UBTH from January 2017 to December 2019 were retrospectively studied. Information on their presentation, clinical management and outcomes of treatment were retrieved from the hospital records library, ward registers, departmental computerized data set and theatre records. The data was analyzed using SPSS version 22. There were 6738 deliveries, 2365 gynaecological admissions and 141 cases of ectopic pregnancy in the period under review. Ectopic pregnancy (EP) constituted 2.1% of all deliveries and 5.97% of all gynaecological admissions. The peak age of incidence was 25 – 29 years. The majority of the patients (58.2%) were single and they were mostly undergraduates (41.8%). The majority (81.6%) presented with ruptured ectopic pregnancy. Shock was the commonest presentation (59.1%), and 60.1% had a blood transfusion. Salpingectomy was the mainstay of treatment (86.3%). For the unruptured cases selected for medical management, the success rate was 84.2%. Ectopic pregnancy is a common gynaecological emergency and still poses a major challenge due to late presentation. Previous induced abortion and pelvic inflammatory disease are the major risk factors for EP. Increasing awareness of prevention, early presentation, and risk of morbidity and mortality will help to reduce this scourge.
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Author Information
  • Department of Obstetrics and Gynaecology, School of Medicine, College of Medical Sciences, University of Benin, Benin City, Nigeria

  • Department of Obstetrics and Gynaecology, Federal Medical Centre, Yenagoa, Nigeria

  • Department of Obstetrics and Gynaecology, School of Medicine, College of Medical Sciences, University of Benin, Benin City, Nigeria

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