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Research Progress in Drug Treatment of Adenomyosis

Received: 16 March 2022    Accepted: 6 April 2022    Published: 20 April 2022
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Abstract

Background: Adenomyosis is caused by endometrial glands and stroma invading the myometrium. It is more common in parturients after the age of 30. At present, there are many drugs for the treatment of adenomyosis, and drug treatment is also one of the important treatments for adenomyosis. Objective: To summarize the drugs that can be used for the treatment of adenomyosis, hoping to be helpful to the clinical treatment. Method: Relevant studies were retrieved from the MEDLINE, Embase, Cochrane Library, CENTRAL and ClinicalTrials.gov. The retrieval time range was from January 2000 to March 2022. English search terms included "(treatment)","(adenomyosis) OR (endometrioma) OR (adenomyoma)". Result: Drug therapy can relieve the clinical symptoms of patients, inhibit the proliferation of lesions, and cooperate with surgical treatment to improve the curative effect. The efficacy and adverse reactions of the drug are closely related to the duration of use. At present, there is no specific drug for the treatment of adenomyosis, and there is a certain degree of recurrence after drug withdrawal. Some clinical scholars have adopted a combination regimen for the treatment of adenomyosis and achieved certain results. Conclusion: About the drug treatment of adenomyosis, it is necessary to personalize the treatment plan by combining the severity of the patients' clinical symptoms, age, fertility needs, patients' economic conditions, whether they can regulate the use of drugs, and the adverse reactions after the use of drugs.

Published in Journal of Gynecology and Obstetrics (Volume 10, Issue 2)
DOI 10.11648/j.jgo.20221002.22
Page(s) 139-143
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Adenomyosis, Drug Treatment, Review

References
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  • APA Style

    Zhenyue Qin, Zhiyong Dong, Junling Liu, Shoufeng Zhang, Huihui Wang, et al. (2022). Research Progress in Drug Treatment of Adenomyosis. Journal of Gynecology and Obstetrics, 10(2), 139-143. https://doi.org/10.11648/j.jgo.20221002.22

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    ACS Style

    Zhenyue Qin; Zhiyong Dong; Junling Liu; Shoufeng Zhang; Huihui Wang, et al. Research Progress in Drug Treatment of Adenomyosis. J. Gynecol. Obstet. 2022, 10(2), 139-143. doi: 10.11648/j.jgo.20221002.22

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    AMA Style

    Zhenyue Qin, Zhiyong Dong, Junling Liu, Shoufeng Zhang, Huihui Wang, et al. Research Progress in Drug Treatment of Adenomyosis. J Gynecol Obstet. 2022;10(2):139-143. doi: 10.11648/j.jgo.20221002.22

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  • @article{10.11648/j.jgo.20221002.22,
      author = {Zhenyue Qin and Zhiyong Dong and Junling Liu and Shoufeng Zhang and Huihui Wang and Mingyue Bao and Weiwei Wei and Ruxia Shi and Jiming Chen and Bairong Xia},
      title = {Research Progress in Drug Treatment of Adenomyosis},
      journal = {Journal of Gynecology and Obstetrics},
      volume = {10},
      number = {2},
      pages = {139-143},
      doi = {10.11648/j.jgo.20221002.22},
      url = {https://doi.org/10.11648/j.jgo.20221002.22},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20221002.22},
      abstract = {Background: Adenomyosis is caused by endometrial glands and stroma invading the myometrium. It is more common in parturients after the age of 30. At present, there are many drugs for the treatment of adenomyosis, and drug treatment is also one of the important treatments for adenomyosis. Objective: To summarize the drugs that can be used for the treatment of adenomyosis, hoping to be helpful to the clinical treatment. Method: Relevant studies were retrieved from the MEDLINE, Embase, Cochrane Library, CENTRAL and ClinicalTrials.gov. The retrieval time range was from January 2000 to March 2022. English search terms included "(treatment)","(adenomyosis) OR (endometrioma) OR (adenomyoma)". Result: Drug therapy can relieve the clinical symptoms of patients, inhibit the proliferation of lesions, and cooperate with surgical treatment to improve the curative effect. The efficacy and adverse reactions of the drug are closely related to the duration of use. At present, there is no specific drug for the treatment of adenomyosis, and there is a certain degree of recurrence after drug withdrawal. Some clinical scholars have adopted a combination regimen for the treatment of adenomyosis and achieved certain results. Conclusion: About the drug treatment of adenomyosis, it is necessary to personalize the treatment plan by combining the severity of the patients' clinical symptoms, age, fertility needs, patients' economic conditions, whether they can regulate the use of drugs, and the adverse reactions after the use of drugs.},
     year = {2022}
    }
    

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  • TY  - JOUR
    T1  - Research Progress in Drug Treatment of Adenomyosis
    AU  - Zhenyue Qin
    AU  - Zhiyong Dong
    AU  - Junling Liu
    AU  - Shoufeng Zhang
    AU  - Huihui Wang
    AU  - Mingyue Bao
    AU  - Weiwei Wei
    AU  - Ruxia Shi
    AU  - Jiming Chen
    AU  - Bairong Xia
    Y1  - 2022/04/20
    PY  - 2022
    N1  - https://doi.org/10.11648/j.jgo.20221002.22
    DO  - 10.11648/j.jgo.20221002.22
    T2  - Journal of Gynecology and Obstetrics
    JF  - Journal of Gynecology and Obstetrics
    JO  - Journal of Gynecology and Obstetrics
    SP  - 139
    EP  - 143
    PB  - Science Publishing Group
    SN  - 2376-7820
    UR  - https://doi.org/10.11648/j.jgo.20221002.22
    AB  - Background: Adenomyosis is caused by endometrial glands and stroma invading the myometrium. It is more common in parturients after the age of 30. At present, there are many drugs for the treatment of adenomyosis, and drug treatment is also one of the important treatments for adenomyosis. Objective: To summarize the drugs that can be used for the treatment of adenomyosis, hoping to be helpful to the clinical treatment. Method: Relevant studies were retrieved from the MEDLINE, Embase, Cochrane Library, CENTRAL and ClinicalTrials.gov. The retrieval time range was from January 2000 to March 2022. English search terms included "(treatment)","(adenomyosis) OR (endometrioma) OR (adenomyoma)". Result: Drug therapy can relieve the clinical symptoms of patients, inhibit the proliferation of lesions, and cooperate with surgical treatment to improve the curative effect. The efficacy and adverse reactions of the drug are closely related to the duration of use. At present, there is no specific drug for the treatment of adenomyosis, and there is a certain degree of recurrence after drug withdrawal. Some clinical scholars have adopted a combination regimen for the treatment of adenomyosis and achieved certain results. Conclusion: About the drug treatment of adenomyosis, it is necessary to personalize the treatment plan by combining the severity of the patients' clinical symptoms, age, fertility needs, patients' economic conditions, whether they can regulate the use of drugs, and the adverse reactions after the use of drugs.
    VL  - 10
    IS  - 2
    ER  - 

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Author Information
  • Graduate School, Dalian Medical University, Dalian, PR China

  • Department of Gynecology, The Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou, PR China

  • Department of Gynecology, The Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou, PR China

  • Graduate School, Dalian Medical University, Dalian, PR China

  • Graduate School, Dalian Medical University, Dalian, PR China

  • Graduate School, Dalian Medical University, Dalian, PR China

  • Department of Gynecology, The Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou, PR China

  • Department of Gynecology, The Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou, PR China

  • Department of Gynecology, The Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou, PR China

  • Department of Gynecology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, PR China

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