PPROM at 15 Weeks of Gestation: A Story of Hope

Aziz Rodolphe; Halimeh Rawad; Feghali Joe

doi:doi:10.11648/j.jgo.20210905.15

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PPROM at 15 Weeks of Gestation: A Story of Hope

Aziz Rodolphe, Halimeh Rawad, Feghali Joe

Published in Journal of Gynecology and Obstetrics (Volume 9, Issue 5)

Received: 18 August 2021 Accepted: 7 September 2021 Published: 30 September 2021

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Abstract

Spontaneous preterm premature rupture of membranes that occurs before 20 weeks of gestation is a rare complication that is usually followed by miscarriage. There are various risk factors, including infection, inflammation, trauma, and it can sometimes be idiopathic. If PPROM happens as early as 15 weeks of gestation, termination of the pregnancy is usually the method of choice. Several risks affect the fetus and the mother if the mother decides to continue her pregnancy. The fetal musculoskeletal, gastrointestinal, respiratory, and nervous systems are mainly affected, and fetal death occurs in most cases. In patients who decide to take the risk and continue their pregnancy, conservative management with antibiotics and monitoring is usually required. The end result is either chorioamnionitis or spontaneous expulsion. This case presents a rare outcome of pregnancy after spontaneous preterm premature rupture of membranes at 15 weeks of gestation and delivery of a healthy living baby at term. The management of this case throughout pregnancy will be presented along with a literature review.

Published in	Journal of Gynecology and Obstetrics (Volume 9, Issue 5)
DOI	10.11648/j.jgo.20210905.15
Page(s)	162-166
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

PPROM, Early Gestation, Conservative Management, Live Baby

References

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[2]	Tchirikov, M., Schlabritz-Loutsevitch, N., Maher, J., Buchmann, J., Naberezhnev, Y., Winarno, A., & Seliger, G. (2017). Mid-trimester preterm premature rupture of membranes (PPROM): etiology, diagnosis, classification, international recommendations of treatment options and outcome. Journal of Perinatal Medicine, 46 (5), 465-488. doi: 10.1515/jpm-2017-0027.
[3]	Mercer, B., 2003. Preterm Premature Rupture of the Membranes. Obstetrics & Gynecology, 101 (1), pp. 178-193.
[4]	Yang, L., Hendricks, S., Taylor, D., Hume, R., Calhoun, B. and Kaufman, H., 2003. Active Expectant Management of Second-Trimester Preterm Premature Rupture of Membranes. Obstetrics & Gynecology, 101 (Supplement), p. 36S.
[5]	Moretti, M. and Sibai, B., 1988. Maternal and perinatal outcome of expectant management of premature rupture of membranes in the midtrimester. American Journal of Obstetrics and Gynecology, 159 (2), pp. 390-396.
[6]	Falk, S., Campbell, L., Lee-Parritz, A., Cohen, A., Ecker, J., Wilkins-Haug, L., & Lieberman, E. (2004). Expectant Management in Spontaneous Preterm Premature Rupture of Membranes between 14 and 24 Weeks' Gestation. Journal of Perinatology, 24 (10), 611-616. doi: 10.1038/sj.jp.7211163.
[7]	Kibel, M., Asztalos, E., Barrett, J., Dunn, M., Tward, C., Pittini, A. and Melamed, N., 2016. Outcomes of Pregnancies Complicated by Preterm Premature Rupture of Membranes Between 20 and 24 Weeks of Gestation. Obstetrics & Gynecology, 128 (2), pp. 313-320.
[8]	Goldenberg, R., Hauth, J. and Andrews, W., 2000. Intrauterine Infection and Preterm Delivery. New England Journal of Medicine, 342 (20), pp. 1500-1507.
[9]	Bloom, S. (2001). Recurrence of preterm birth in singleton and twin pregnancies. Obstetrics & Gynecology, 98 (3), 379-385. doi: 10.1016/s0029-7844(01)01466-1.
[10]	Lewis, D., Adair, C., Weeks, J., Barrilleaux, P., Edwards, M. and Garite, T., 1999. A randomized clinical trial of daily nonstress testing versus biophysical profile in the management of preterm premature rupture of membranes. American Journal of Obstetrics and Gynecology, 181 (6), pp. 1495-1499.
[11]	Asadi N, Faraji A, Keshavarzi A, Akbarzadeh-Jahromi M, Yoosefi S. Predictive value of procalcitonin, C-reactive protein, and white blood cells for chorioamnionitis among women with preterm premature rupture of membranes. International Journal of Gynecology & Obstetrics. 2019; 147 (1): 83-88.
[12]	Zaidi H, Lamalmi N, Lahlou L, Slaoui M, Barkat A, Alamrani S et al. Clinical predictive factors of histological chorioamnionitis: case-control study. Heliyon. 2020; 6 (12): e05698.
[13]	Redline R, Faye-Petersen O, Heller D, Qureshi F, Savell V, Vogler C. Amniotic Infection Syndrome: Nosology and Reproducibility of Placental Reaction Patterns. Pediatric and Developmental Pathology. 2003; 6 (5): 435-448.
[14]	Mura T, Picaud J, Larroque B, Galtier F, Marret S, Roze J et al. Cognitive Impairment at Age 5 Years in Very Preterm Infants Born Following Premature Rupture of Membranes. The Journal of Pediatrics. 2013; 163 (2): 435-440. e2.
[15]	Manuck T, Maclean C, Silver R, Varner M. Preterm premature rupture of membranes: does the duration of latency influence perinatal outcomes?. American Journal of Obstetrics and Gynecology. 2009; 201 (4): 414. e1-414. e6.
[16]	Melamed N, Hadar E, Ben-Haroush A, Kaplan B, Yogev Y. Factors affecting the duration of the latency period in preterm premature rupture of membranes. The Journal of Maternal-Fetal & Neonatal Medicine. 2009; 22 (11): 1051-1056.

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APA Style

Aziz Rodolphe, Halimeh Rawad, Feghali Joe. (2021). PPROM at 15 Weeks of Gestation: A Story of Hope. Journal of Gynecology and Obstetrics, 9(5), 162-166. https://doi.org/10.11648/j.jgo.20210905.15

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ACS Style

Aziz Rodolphe; Halimeh Rawad; Feghali Joe. PPROM at 15 Weeks of Gestation: A Story of Hope. J. Gynecol. Obstet. 2021, 9(5), 162-166. doi: 10.11648/j.jgo.20210905.15

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AMA Style

Aziz Rodolphe, Halimeh Rawad, Feghali Joe. PPROM at 15 Weeks of Gestation: A Story of Hope. J Gynecol Obstet. 2021;9(5):162-166. doi: 10.11648/j.jgo.20210905.15

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@article{10.11648/j.jgo.20210905.15,
  author = {Aziz Rodolphe and Halimeh Rawad and Feghali Joe},
  title = {PPROM at 15 Weeks of Gestation: A Story of Hope},
  journal = {Journal of Gynecology and Obstetrics},
  volume = {9},
  number = {5},
  pages = {162-166},
  doi = {10.11648/j.jgo.20210905.15},
  url = {https://doi.org/10.11648/j.jgo.20210905.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20210905.15},
  abstract = {Spontaneous preterm premature rupture of membranes that occurs before 20 weeks of gestation is a rare complication that is usually followed by miscarriage. There are various risk factors, including infection, inflammation, trauma, and it can sometimes be idiopathic. If PPROM happens as early as 15 weeks of gestation, termination of the pregnancy is usually the method of choice. Several risks affect the fetus and the mother if the mother decides to continue her pregnancy. The fetal musculoskeletal, gastrointestinal, respiratory, and nervous systems are mainly affected, and fetal death occurs in most cases. In patients who decide to take the risk and continue their pregnancy, conservative management with antibiotics and monitoring is usually required. The end result is either chorioamnionitis or spontaneous expulsion. This case presents a rare outcome of pregnancy after spontaneous preterm premature rupture of membranes at 15 weeks of gestation and delivery of a healthy living baby at term. The management of this case throughout pregnancy will be presented along with a literature review.},
 year = {2021}
}

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TY - JOUR
T1 - PPROM at 15 Weeks of Gestation: A Story of Hope
AU - Aziz Rodolphe
AU - Halimeh Rawad
AU - Feghali Joe
Y1 - 2021/09/30
PY - 2021
N1 - https://doi.org/10.11648/j.jgo.20210905.15
DO - 10.11648/j.jgo.20210905.15
T2 - Journal of Gynecology and Obstetrics
JF - Journal of Gynecology and Obstetrics
JO - Journal of Gynecology and Obstetrics
SP - 162
EP - 166
PB - Science Publishing Group
SN - 2376-7820
UR - https://doi.org/10.11648/j.jgo.20210905.15
AB - Spontaneous preterm premature rupture of membranes that occurs before 20 weeks of gestation is a rare complication that is usually followed by miscarriage. There are various risk factors, including infection, inflammation, trauma, and it can sometimes be idiopathic. If PPROM happens as early as 15 weeks of gestation, termination of the pregnancy is usually the method of choice. Several risks affect the fetus and the mother if the mother decides to continue her pregnancy. The fetal musculoskeletal, gastrointestinal, respiratory, and nervous systems are mainly affected, and fetal death occurs in most cases. In patients who decide to take the risk and continue their pregnancy, conservative management with antibiotics and monitoring is usually required. The end result is either chorioamnionitis or spontaneous expulsion. This case presents a rare outcome of pregnancy after spontaneous preterm premature rupture of membranes at 15 weeks of gestation and delivery of a healthy living baby at term. The management of this case throughout pregnancy will be presented along with a literature review.
VL - 9
IS - 5
ER -

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Author Information

Aziz Rodolphe

Department of Obstetrics and Gynecology, Saint George Hospital University Medical Center, Beirut, Lebanon
Halimeh Rawad

Department of Obstetrics and Gynecology, Saint George Hospital University Medical Center, Beirut, Lebanon
Feghali Joe

Department of Obstetrics and Gynecology, Saint George Hospital University Medical Center, Beirut, Lebanon

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Plain Text BibTeX RIS

APA Style

Aziz Rodolphe, Halimeh Rawad, Feghali Joe. (2021). PPROM at 15 Weeks of Gestation: A Story of Hope. Journal of Gynecology and Obstetrics, 9(5), 162-166. https://doi.org/10.11648/j.jgo.20210905.15

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ACS Style

Aziz Rodolphe; Halimeh Rawad; Feghali Joe. PPROM at 15 Weeks of Gestation: A Story of Hope. J. Gynecol. Obstet. 2021, 9(5), 162-166. doi: 10.11648/j.jgo.20210905.15

Copy | Download

AMA Style

Aziz Rodolphe, Halimeh Rawad, Feghali Joe. PPROM at 15 Weeks of Gestation: A Story of Hope. J Gynecol Obstet. 2021;9(5):162-166. doi: 10.11648/j.jgo.20210905.15

Copy | Download

@article{10.11648/j.jgo.20210905.15,
  author = {Aziz Rodolphe and Halimeh Rawad and Feghali Joe},
  title = {PPROM at 15 Weeks of Gestation: A Story of Hope},
  journal = {Journal of Gynecology and Obstetrics},
  volume = {9},
  number = {5},
  pages = {162-166},
  doi = {10.11648/j.jgo.20210905.15},
  url = {https://doi.org/10.11648/j.jgo.20210905.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20210905.15},
  abstract = {Spontaneous preterm premature rupture of membranes that occurs before 20 weeks of gestation is a rare complication that is usually followed by miscarriage. There are various risk factors, including infection, inflammation, trauma, and it can sometimes be idiopathic. If PPROM happens as early as 15 weeks of gestation, termination of the pregnancy is usually the method of choice. Several risks affect the fetus and the mother if the mother decides to continue her pregnancy. The fetal musculoskeletal, gastrointestinal, respiratory, and nervous systems are mainly affected, and fetal death occurs in most cases. In patients who decide to take the risk and continue their pregnancy, conservative management with antibiotics and monitoring is usually required. The end result is either chorioamnionitis or spontaneous expulsion. This case presents a rare outcome of pregnancy after spontaneous preterm premature rupture of membranes at 15 weeks of gestation and delivery of a healthy living baby at term. The management of this case throughout pregnancy will be presented along with a literature review.},
 year = {2021}
}

Copy | Download