Investigation and Analysis of the Information Available for Pregnant and Lactating Women in 308 Antipsychotic Package Inserts

Xiaoru Yang; Jufeng Li; Jieyi Zhou; Xiaofei Feng; Jiawen Huang

doi:doi:10.11648/j.jgo.20210903.15

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Investigation and Analysis of the Information Available for Pregnant and Lactating Women in 308 Antipsychotic Package Inserts

Xiaoru Yang, Jufeng Li, Jieyi Zhou, Xiaofei Feng, Jiawen Huang

Published in Journal of Gynecology and Obstetrics (Volume 9, Issue 3)

Received: 8 June 2021 Accepted: 18 June 2021 Published: 25 June 2021

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Abstract

Background: Package insert is an important tool to provide safe and reasonable guidance for pregnant and lactating women. Methods: The information on pregnant women in 308 package inserts of 38 kinds of antipsychotics on the market was analyzed. Results: 287 (93.18%) package inserts in the 308 antipsychotics provide drug use guiding information for pregnant women, while 150 (48.70%) of them made it clear that the drug could be used normally, cautiously or forbidden on pregnant women. 137 (44.48%) of them used different expressions. There were 64 (20.78%) instructions that made it clear that the drug could be used normally, cautiously or forbidden on lactation women. 81 (26.30%) instructions are recommended to stop breastfeeding. 142 (46.10%) instructions for breastfeeding women used different expressions. Contradictions were found in 23.53% drugs for pregnant women and 29.41% for lactation women. Conclusion: There are some problems with drug information on pregnant women in package inserts，such as inadequate information and inaccurate description. To ensure safer use, the package inserts of medicines should be further improved.

Published in	Journal of Gynecology and Obstetrics (Volume 9, Issue 3)
DOI	10.11648/j.jgo.20210903.15
Page(s)	79-83
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Package Inserts, Antipsychotics, Pregnant Women, Lactating Women

References

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APA Style

Xiaoru Yang, Jufeng Li, Jieyi Zhou, Xiaofei Feng, Jiawen Huang. (2021). Investigation and Analysis of the Information Available for Pregnant and Lactating Women in 308 Antipsychotic Package Inserts. Journal of Gynecology and Obstetrics, 9(3), 79-83. https://doi.org/10.11648/j.jgo.20210903.15

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ACS Style

Xiaoru Yang; Jufeng Li; Jieyi Zhou; Xiaofei Feng; Jiawen Huang. Investigation and Analysis of the Information Available for Pregnant and Lactating Women in 308 Antipsychotic Package Inserts. J. Gynecol. Obstet. 2021, 9(3), 79-83. doi: 10.11648/j.jgo.20210903.15

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AMA Style

Xiaoru Yang, Jufeng Li, Jieyi Zhou, Xiaofei Feng, Jiawen Huang. Investigation and Analysis of the Information Available for Pregnant and Lactating Women in 308 Antipsychotic Package Inserts. J Gynecol Obstet. 2021;9(3):79-83. doi: 10.11648/j.jgo.20210903.15

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@article{10.11648/j.jgo.20210903.15,
  author = {Xiaoru Yang and Jufeng Li and Jieyi Zhou and Xiaofei Feng and Jiawen Huang},
  title = {Investigation and Analysis of the Information Available for Pregnant and Lactating Women in 308 Antipsychotic Package Inserts},
  journal = {Journal of Gynecology and Obstetrics},
  volume = {9},
  number = {3},
  pages = {79-83},
  doi = {10.11648/j.jgo.20210903.15},
  url = {https://doi.org/10.11648/j.jgo.20210903.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20210903.15},
  abstract = {Background: Package insert is an important tool to provide safe and reasonable guidance for pregnant and lactating women. Methods: The information on pregnant women in 308 package inserts of 38 kinds of antipsychotics on the market was analyzed. Results: 287 (93.18%) package inserts in the 308 antipsychotics provide drug use guiding information for pregnant women, while 150 (48.70%) of them made it clear that the drug could be used normally, cautiously or forbidden on pregnant women. 137 (44.48%) of them used different expressions. There were 64 (20.78%) instructions that made it clear that the drug could be used normally, cautiously or forbidden on lactation women. 81 (26.30%) instructions are recommended to stop breastfeeding. 142 (46.10%) instructions for breastfeeding women used different expressions. Contradictions were found in 23.53% drugs for pregnant women and 29.41% for lactation women. Conclusion: There are some problems with drug information on pregnant women in package inserts，such as inadequate information and inaccurate description. To ensure safer use, the package inserts of medicines should be further improved.},
 year = {2021}
}

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TY  - JOUR
T1  - Investigation and Analysis of the Information Available for Pregnant and Lactating Women in 308 Antipsychotic Package Inserts
AU  - Xiaoru Yang
AU  - Jufeng Li
AU  - Jieyi Zhou
AU  - Xiaofei Feng
AU  - Jiawen Huang
Y1  - 2021/06/25
PY  - 2021
N1  - https://doi.org/10.11648/j.jgo.20210903.15
DO  - 10.11648/j.jgo.20210903.15
T2  - Journal of Gynecology and Obstetrics
JF  - Journal of Gynecology and Obstetrics
JO  - Journal of Gynecology and Obstetrics
SP  - 79
EP  - 83
PB  - Science Publishing Group
SN  - 2376-7820
UR  - https://doi.org/10.11648/j.jgo.20210903.15
AB  - Background: Package insert is an important tool to provide safe and reasonable guidance for pregnant and lactating women. Methods: The information on pregnant women in 308 package inserts of 38 kinds of antipsychotics on the market was analyzed. Results: 287 (93.18%) package inserts in the 308 antipsychotics provide drug use guiding information for pregnant women, while 150 (48.70%) of them made it clear that the drug could be used normally, cautiously or forbidden on pregnant women. 137 (44.48%) of them used different expressions. There were 64 (20.78%) instructions that made it clear that the drug could be used normally, cautiously or forbidden on lactation women. 81 (26.30%) instructions are recommended to stop breastfeeding. 142 (46.10%) instructions for breastfeeding women used different expressions. Contradictions were found in 23.53% drugs for pregnant women and 29.41% for lactation women. Conclusion: There are some problems with drug information on pregnant women in package inserts，such as inadequate information and inaccurate description. To ensure safer use, the package inserts of medicines should be further improved.
VL  - 9
IS  - 3
ER  -

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Author Information

Xiaoru Yang

Department of Pharmacy, First Affiliated Hospital, Jinan University, Guangzhou, China
Jufeng Li

Department of Pharmacy, First Affiliated Hospital, Jinan University, Guangzhou, China
Jieyi Zhou

Department of Pharmacy, First Affiliated Hospital, Jinan University, Guangzhou, China
Xiaofei Feng

Department of Pharmacy, First Affiliated Hospital, Jinan University, Guangzhou, China
Jiawen Huang

Department of Pharmacy, First Affiliated Hospital, Jinan University, Guangzhou, China

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Plain Text BibTeX RIS

APA Style

Xiaoru Yang, Jufeng Li, Jieyi Zhou, Xiaofei Feng, Jiawen Huang. (2021). Investigation and Analysis of the Information Available for Pregnant and Lactating Women in 308 Antipsychotic Package Inserts. Journal of Gynecology and Obstetrics, 9(3), 79-83. https://doi.org/10.11648/j.jgo.20210903.15

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ACS Style

Xiaoru Yang; Jufeng Li; Jieyi Zhou; Xiaofei Feng; Jiawen Huang. Investigation and Analysis of the Information Available for Pregnant and Lactating Women in 308 Antipsychotic Package Inserts. J. Gynecol. Obstet. 2021, 9(3), 79-83. doi: 10.11648/j.jgo.20210903.15

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AMA Style

Xiaoru Yang, Jufeng Li, Jieyi Zhou, Xiaofei Feng, Jiawen Huang. Investigation and Analysis of the Information Available for Pregnant and Lactating Women in 308 Antipsychotic Package Inserts. J Gynecol Obstet. 2021;9(3):79-83. doi: 10.11648/j.jgo.20210903.15

Copy | Download

@article{10.11648/j.jgo.20210903.15,
  author = {Xiaoru Yang and Jufeng Li and Jieyi Zhou and Xiaofei Feng and Jiawen Huang},
  title = {Investigation and Analysis of the Information Available for Pregnant and Lactating Women in 308 Antipsychotic Package Inserts},
  journal = {Journal of Gynecology and Obstetrics},
  volume = {9},
  number = {3},
  pages = {79-83},
  doi = {10.11648/j.jgo.20210903.15},
  url = {https://doi.org/10.11648/j.jgo.20210903.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20210903.15},
  abstract = {Background: Package insert is an important tool to provide safe and reasonable guidance for pregnant and lactating women. Methods: The information on pregnant women in 308 package inserts of 38 kinds of antipsychotics on the market was analyzed. Results: 287 (93.18%) package inserts in the 308 antipsychotics provide drug use guiding information for pregnant women, while 150 (48.70%) of them made it clear that the drug could be used normally, cautiously or forbidden on pregnant women. 137 (44.48%) of them used different expressions. There were 64 (20.78%) instructions that made it clear that the drug could be used normally, cautiously or forbidden on lactation women. 81 (26.30%) instructions are recommended to stop breastfeeding. 142 (46.10%) instructions for breastfeeding women used different expressions. Contradictions were found in 23.53% drugs for pregnant women and 29.41% for lactation women. Conclusion: There are some problems with drug information on pregnant women in package inserts，such as inadequate information and inaccurate description. To ensure safer use, the package inserts of medicines should be further improved.},
 year = {2021}
}

Copy | Download

TY  - JOUR
T1  - Investigation and Analysis of the Information Available for Pregnant and Lactating Women in 308 Antipsychotic Package Inserts
AU  - Xiaoru Yang
AU  - Jufeng Li
AU  - Jieyi Zhou
AU  - Xiaofei Feng
AU  - Jiawen Huang
Y1  - 2021/06/25
PY  - 2021
N1  - https://doi.org/10.11648/j.jgo.20210903.15
DO  - 10.11648/j.jgo.20210903.15
T2  - Journal of Gynecology and Obstetrics
JF  - Journal of Gynecology and Obstetrics
JO  - Journal of Gynecology and Obstetrics
SP  - 79
EP  - 83
PB  - Science Publishing Group
SN  - 2376-7820
UR  - https://doi.org/10.11648/j.jgo.20210903.15
AB  - Background: Package insert is an important tool to provide safe and reasonable guidance for pregnant and lactating women. Methods: The information on pregnant women in 308 package inserts of 38 kinds of antipsychotics on the market was analyzed. Results: 287 (93.18%) package inserts in the 308 antipsychotics provide drug use guiding information for pregnant women, while 150 (48.70%) of them made it clear that the drug could be used normally, cautiously or forbidden on pregnant women. 137 (44.48%) of them used different expressions. There were 64 (20.78%) instructions that made it clear that the drug could be used normally, cautiously or forbidden on lactation women. 81 (26.30%) instructions are recommended to stop breastfeeding. 142 (46.10%) instructions for breastfeeding women used different expressions. Contradictions were found in 23.53% drugs for pregnant women and 29.41% for lactation women. Conclusion: There are some problems with drug information on pregnant women in package inserts，such as inadequate information and inaccurate description. To ensure safer use, the package inserts of medicines should be further improved.
VL  - 9
IS  - 3
ER  -

Copy | Download